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Insulin-like growth factor II precursor gene organization in relation to insulin gene family

✍ Scribed by Dull, Thomas J.; Gray, Alane; Hayflick, Joel S.; Ullrich, Axel


Book ID
109736392
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
593 KB
Volume
310
Category
Article
ISSN
0028-0836

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In this study messenger ribonucleic acid (mRNA) and DNA of five Wilms tumours were investigated. As expected, the level of insulin-like growth factor (IGF) II-mRNA was elevated up to 50 times in tumour tissue as compared to normal adjacent kidney tissue. In addition, genomic DNA was isolated and dig