Insulin-like growth factor I stimulates transcription of the c-jun proto-oncogene in Balbc 3T3 cells
β Scribed by Shean-Tai Chiou; Wen-Chang Chang
- Book ID
- 115764949
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 993 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## I 12, lapan The present study was conducted to determine the cell-cycle dependency of various actions of IGF-I in Balbk 3T3 cells. When autophosphorylation of the IGF-I receptor was determined in [ '2P]-labelled cells, IGF-I increased radioactivity in a 100 K-Da phosphoprotein, presumably p-sub
Insulin-like growth factor (IGF) I is an autocrine regulator of bone remodeling which inhibits bone collagen degradation and interstitial collagenase 3 mRNA levels. The mechanism of this inhibitory effect on collagenase 3 expression is not known. We tested the effects of IGF I on collagenase 3 gene