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Insulin-like growth factor-I stimulates H4II rat hepatoma cell proliferation: Dominant role of PI-3′K/Akt signaling

✍ Scribed by Catherine Alexia; Pascal Fourmatgeat; Danièle Delautier; André Groyer

Book ID: 118506382
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 512 KB
Volume: 312
Category: Article
ISSN: 0014-4827
DOI: 10.1016/j.yexcr.2006.01.007

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## Abstract The role of regucalcin, a regulatory protein in intracellular signaling pathway, in cell death was investigated by using the cloned rat hepatoma H4‐II‐E cells overexpressing regucalcin. The hepatoma cells (wild‐type) and stable regucalcin/pCXN2 transfectants were cultured for 72 h in a