Neuroblastoma is a childhood tumor of the peripheral nervous system that remains largely uncurable by conventional methods. Mannitol induces apoptosis in neuroblastoma cell types and insulin-like growth factor I (IGF-I) protects these cells from hyperosmotic-induced apoptosis by affecting apoptosis-
Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death
✍ Scribed by Christopher C. Matthews; Eva L. Feldman
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 623 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
growth factor is important to neuronal survival under adverse physiological conditions.
📜 SIMILAR VOLUMES
## Abstract Myristoylated alanine‐rich C kinase substrate (MARCKS) has been suggested to be involved in various aspects of neuronal cell differentiation, including neurite outgrowth. However, the precise mechanisms by which MARCKS phosphorylation is regulated, and how MARCKS contributes to neurite
## Abstract The capsaicin receptor, transient receptor potential, vanilloid type 1 (TRPV1), is a Ca^2+^‐permeable ion channel activated by noxious stimuli eliciting pain. Several reports have shown modulation of TRPV1 activity and expression by neuronal growth factors. Here, we study the long‐term
## Abstract The insulin‐like growth factor (IGF) system is a key regulator of cell growth, survival and differentiation, and these functions are co‐modulated by other growth factors including fibroblast growth factor‐2 (FGF‐2). To investigate IGF/FGF interactions in neuronal cells, we employed neur