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Insulin-like growth factor-I regulates GPER expression and function in cancer cells

✍ Scribed by De Marco, P; Bartella, V; Vivacqua, A; Lappano, R; Santolla, M F; Morcavallo, A; Pezzi, V; Belfiore, A; Maggiolini, M

Book ID
115514757
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
785 KB
Volume
32
Category
Article
ISSN
0950-9232

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Insulin-like growth factor I regulates renal development in rodents
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Blocking the action of insulin-like growth factor I (IGF I) impairs kidney development in vitro. However, no renal developmental abnormalities have been reported in newborn transgenic mice that do not express IGF I (Igf1 Οͺ/Οͺ ) mice. Ninety-five percent of Igf1 Οͺ/Οͺ mice die immediately following birt