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Insulin-Like Growth Factor-I Plays a Pathogenetic Role in Diabetic Retinopathy

✍ Scribed by Vassiliki Poulaki; Antonia M. Joussen; Nicholas Mitsiades; Constantine S. Mitsiades; Eirini F. Iliaki; Anthony P. Adamis

Book ID
117021591
Publisher
American Society for Investigative Pathology
Year
2004
Tongue
English
Weight
815 KB
Volume
165
Category
Article
ISSN
0002-9440

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Multiple factors contribute to the growth retardation which is a characteristic feature of uncontrolled diabetes. In this report we have examined the effects of streptozotocin-induced (STZ) diabetes on expression of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-