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Insulin-like growth factor-I induces CLU expression through Twist1 to promote prostate cancer growth

✍ Scribed by Takeuchi, Ario; Shiota, Masaki; Beraldi, Eliana; Thaper, Daksh; Takahara, Kiyoshi; Ibuki, Naokazu; Pollak, Michael; Cox, Michael E.; Naito, Seiji; Gleave, Martin E.; Zoubeidi, Amina


Book ID
121494946
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
723 KB
Volume
384
Category
Article
ISSN
0303-7207

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## Abstract Targeting stroma in tumor tissues is an attractive new strategy for cancer treatment. We developed __in vitro__ coculture system, in which the growth of human prostate cancer DU‐145 cells is stimulated by prostate stromal cells (PrSC) through insulin‐like growth factor I (IGF‐I). Using