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Insulin-like growth factor-I (IGF-I) protects cultured equine Leydig cells from undergoing apoptosis

โœ Scribed by M.J. Yoon; J.F. Roser

Book ID
118415590
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
258 KB
Volume
122
Category
Article
ISSN
0378-4320

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Using insulin-like growth factor-I (IGF-I)-overexpressing transgenic (Tg) mice as a model, we have shown that IGF-I promotes myelination by increasing the number of oligodendrocytes and stimulating the expression of myelin-specific protein genes. In the present study, we investigated whether IGF-I p