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Insulin-like growth factor binding protein-3 prevents retinoid receptor heterodimerization: implications for retinoic acid-sensitivity in human breast cancer cells

✍ Scribed by Lynette J Schedlich; Michelle K O’Han; Gary M Leong; Robert C Baxter


Book ID
116287733
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
186 KB
Volume
314
Category
Article
ISSN
0006-291X

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Variability in response to chemotherapy is poorly understood. Paclitaxel-induced apoptosis was assessed in human Hs578T breast cancer cells, using the MTT assay, cell counting, morphological features and flow cytometry. Pre-dosing cells with non-glycosylated insulin-like growth factor binding protei