Insulin-like growth factor binding protein-3 is secreted as a phosphoprotein by human breast cancer cells
β Scribed by Scott T Pattison; Susan Fanayan; Janet L Martin
- Book ID
- 117464263
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 350 KB
- Volume
- 156
- Category
- Article
- ISSN
- 0303-7207
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The mitogenic effects of insulin-like growth factors (IGFs) are regulated by a family of insulin-like growth factor binding proteins (IGFBPs). One member of this family, IGFBP-3, mediates the growth-inhibitory and apoptosis-inducing effects of a number of growth factors and hormones such as transfor