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Insulin-like growth factor binding protein-3 increases intracellular calcium concentrations in MCF-7 breast carcinoma cells

โœ Scribed by Jean-Marc Ricort; Alain Lombet; Claudine Lassarre; Michel Binoux


Book ID
117104596
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
346 KB
Volume
527
Category
Article
ISSN
0014-5793

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The mitogenic effects of insulin-like growth factors (IGFs) are regulated by a family of insulin-like growth factor binding proteins (IGFBPs). One member of this family, IGFBP-3, mediates the growth-inhibitory and apoptosis-inducing effects of a number of growth factors and hormones such as transfor