Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-κB

Insulin-like growth factor binding prote

Insulin-like growth factor binding protein-3 (IGFBP-3) potentiates paclitaxel-induced apoptosis in human breast cancer cells

✍ C.A. Fowler; C.M. Perks; P.V. Newcomb; P.B. Savage; J.R. Farndon; J.M.P. Holly 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 145 KB 👁 2 views

Variability in response to chemotherapy is poorly understood. Paclitaxel-induced apoptosis was assessed in human Hs578T breast cancer cells, using the MTT assay, cell counting, morphological features and flow cytometry. Pre-dosing cells with non-glycosylated insulin-like growth factor binding protei