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Insulin-like growth factor binding protein-2 alters the sensitivity of breast cancer cells to chemotherapy

โœ Scribed by EJ Foulstone, JM Holly, L Zeng, ZE Winters, CM Perks


Book ID
120699680
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
390 KB
Volume
12
Category
Article
ISSN
1465-5411

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The mitogenic effects of insulin-like growth factors (IGFs) are regulated by a family of insulin-like growth factor binding proteins (IGFBPs). One member of this family, IGFBP-3, mediates the growth-inhibitory and apoptosis-inducing effects of a number of growth factors and hormones such as transfor