Insulin-Like Growth Factor 1 Receptor Promotes the Growth and Chemoresistance of Pancreatic Cancer
β Scribed by Tian, Xiaodong; Hao, Kun; Qin, Changfu; Xie, Kun; Xie, Xuehai; Yang, Yinmo
- Book ID
- 120383974
- Publisher
- Springer US
- Year
- 2013
- Tongue
- English
- Weight
- 658 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0163-2116
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In the current study the authors have investigated whether human primary breast cancer specimens contain insulin-like growth factor-1 (IGF-1) receptors (IGF-1-R) or IGF-1-like activities. Simultaneously, epidermal growth factor (EGF) receptors (EGF-R) and cytosolic estrogen receptor (ER), progestero
## Abstract Recent epidemiological studies have shown that high serum levels of insulinβlike growth factorβI (IGFβI) are associated with an increased risk of lung, colon, breast and prostate cancer. Since very few studies have addressed the role of serum levels of IGFβI in the development of pancre