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Insulin-like growth factor-1 promotes drug resistance and expression of c-H-ras and P-glycoprotein in MCLM colon cancer cells


Book ID
116104706
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
104 KB
Volume
64
Category
Article
ISSN
0167-0115

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Insulin-like growth factor-I promotes mu
✍ Yan-Shi Guo; Gui-Fang Jin; Clifford W. Houston; James C. Thompson; Courtney M. T πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 259 KB πŸ‘ 1 views

Insulin-like growth factor-I (IGF-I) is known as a potent mitogen for a variety of cell types, including colon cancer cell lines. The objective of this study was to determine the effect of IGF-I on cell death induced by cytotoxic agents actinomycin D (Act-D), lovastatin (LOV), and doxorubicin (DOX)