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Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells

✍ Scribed by Haitao Wang; Qishan Zhang; Lang Zhang; Peter J. Little; Xiaochun Xie; Qian Meng; Yannan Ren; Lihua Zhou; Guoquan Gao; Remi Quirion; Wenhua Zheng

Book ID
116774061
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
585 KB
Volume
516
Category
Article
ISSN
0304-3940

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Insulin-like growth factor 1 prevents ne
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## Abstract Corticosterone (CORT) is well known to induce neuronal damage in various brain regions including the hippocampus, but the precise mechanism(s) of action underlying these effects has yet to be fully established. Insulin‐like growth factor‐1 (IGF‐1) is a trophic factor promoting cell surv