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Insulin-like growth factor-1 causes a switch-like reduction of endogenous growth hormone mRNA in rat MtT/S somatotroph cells

✍ Scribed by Ty C. Voss; Teresa M. Mangin; David L. Hurley


Book ID
111637565
Publisher
Springer
Year
2000
Tongue
English
Weight
164 KB
Volume
13
Category
Article
ISSN
0969-711X

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## Abstract ## Objective To determine the effects of chronic deficiency of growth hormone (GH) and insulin‐like growth factor 1 (IGF‐1) on osteoarthritis (OA) severity. ## Methods Thirty‐five rats were divided into 4 treatment groups at 4 weeks of age: 1 control group (normal GH/IGF‐1 levels [he