Insulin in the brain: There and back aga
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William A. Banks; Joshua B. Owen; Michelle A. Erickson
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Article
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2012
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Elsevier Science
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English
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Insulin performs unique functions within the CNS. Produced nearly exclusively by the pancreas, insulin crosses the blood-brain barrier (BBB) using a saturable transporter, affecting feeding and cognition through CNS mechanisms largely independent of glucose utilization. Whereas peripheral insulin ac