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Insulin binding and biological activities in the FRTL-5 rat thyroid cell line

✍ Scribed by Vincenzo Trischitta; Giuseppe Damante; Daniela Foti; Sebastiano Filetti

Book ID
118949494
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
519 KB
Volume
36
Category
Article
ISSN
1532-8600

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The aim of the present study was to investigate the mechanisms regulating endothelin-1 (ET-1) secretion in rat thyroid FRTL-5 cells. ET-1 was found to be secreted after stimulation with adenosine and ATP. The release of ET-1 was sensitive to pertussis toxin, indicating a role of G-proteins in the st