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Insulin attenuates atrophy of unweighted soleus muscle by amplified inhibition of protein degradation

โœ Scribed by Marc E. Tischler; Soisungwan Satarug; Anders Aannestad; Kathryn A. Munoz; Erik J. Henriksen

Book ID
117180232
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
884 KB
Volume
46
Category
Article
ISSN
1532-8600

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Cycloheximide (20-200 mg/l) did not affect basal D-[U-14C]xylose uptake by rat soleus muscle (2.4 +/- 0.2 mumol . g-1 . h-1). However, the stimulatory effect of insulin on sugar transport was progressively reduced from 375% above basal in control muscles to 170% in muscles exposed to 200 mg cyclohex