The prodromal phase of type 1 diabetes is characterised by the appearance of multiple islet-cell related autoantibodies (Aab). The major target antigens are islet-cell antigen, glutamic acid decarboxylase (GAD), protein-tyrosine phosphatase-2 (IA-2) and insulin. Insulin autoantibodies (IAA), in cont
Insulin as a key autoantigen in the development of type 1 diabetes
โ Scribed by Maki Nakayama
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 112 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1520-7552
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๐ SIMILAR VOLUMES
It is well established that peripheral insulin sensitivity is a critical factor in the aetiology of non-insulin dependent (Type 2) diabetes mellitus (NIDDM). Insulin resistance may also play a role at various stages in the natural history of insulin dependent (Type 1) diabetes (IDDM) and this was th
The incidence of Type 1 (insulin-dependent) diabetes mellitus among Moroccan children aged (0-19 years) in The Netherlands was determined. Point of reference was the data derived from the second nationwide incidence study on Type 1 diabetes among children under 20 years of age. In that study the inc