𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Instrumental biosensors: new perspectives for the analysis of biomolecular interactions

✍ Scribed by E.C. Nice; B. Catimel

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
394 KB
Volume
21
Category
Article
ISSN
0265-9247

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✦ Synopsis

The use of instrumental biosensors in basic research to measure biomolecular interactions in real time is increasing exponentially. Applications include proteinprotein, protein-peptide, DNA-protein, DNA-DNA, and lipid-protein interactions. Such techniques have been applied to, for example, antibody-antigen, receptorligand, signal transduction, and nuclear receptor studies. This review outlines the principles of two of the most commonly used instruments and highlights specific operating parameters that will assist in optimising experimental design, data generation, and analysis.

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