✦ LIBER ✦

Installation of 12b-substituents onto indolo[2,3-a]quinolizidin-2-ones and application to pentacyclic alkaloid synthesis

✍ Scribed by Jie Jack Li; Bharat.K. Trivedi; J.Ronald Rubin; Bruce D. Roth

Book ID: 104259695
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 225 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01293-3

No coin nor oath required. For personal study only.

✦ Synopsis

12b-Substituted indolol2,3-a]quinolizidin-2-ones 5 are synthesized by treatment of Grignard reagents with O-acetyl iminium salt 4 generated by treating cyclic enaminoketone 3 with acetyl chloride. Subsequent Robinson annulation employing the Stork enamine protocol provided rac-3-phenyl-15,16dehydroreserpone.

📜 SIMILAR VOLUMES

ChemInform Abstract: Installation of 12b

ChemInform Abstract: Installation of 12b-Substituents onto Indolo[2,3-a]quinolizidin-2-ones and Application to Pentacyclic Alkaloid Synthesis.

✍ J. J. LI; B. K. TRIVEDI; J. R. RUBIN; B. D. ROTH 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

ChemInform Abstract: Synthesis of Pentac

ChemInform Abstract: Synthesis of Pentacyclic Ring Systems, Indolo[2,3-a][1,2]oxazino[5,6-i]quinolizine and Indolo[2,3-a]pyrano[3,2-i]quinolizine, and Their Application for the Synthesis of Eburnamine-Vincamine Alkaloids.

✍ Andras Nemes; et al. et al. 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Pd(0)-Catalyzed Tandem Deprotection/Cycl

Pd(0)-Catalyzed Tandem Deprotection/Cyclization of Tetrahydro-β-carbolines on Allenes: Application to the Synthesis of Indolo[2,3- a ]quinolizidines

✍ Gobé, Valerian; Guinchard, Xavier 📂 Article 📅 2014 🏛 American Chemical Society 🌐 English ⚖ 933 KB

Stereoselective addition reactions of ch

Stereoselective addition reactions of chiral .alpha.-sulfinyl ketimine anions with ene esters. Facile asymmetric synthesis of indolo[2,3-a]quinolizidine and yohimbanoid alkaloids [Erratum to document cited in CA112(1):7775w]

✍ Hua, Duy H.; Bharathi, S. Narasimha; Takusagawa, Fusao; Tsujimoto, Atsuko; Panan 📂 Article 📅 1991 🏛 American Chemical Society 🌐 English ⚖ 129 KB

Novel Stereoconvergent Transformation of

Novel Stereoconvergent Transformation of 1,2a-Disubstituted 1,2,2a,8b-Tetrahydro-3H-benzo[b]cyclobuta[d]pyran-3-ones to 1,3-Disubstituted 1,2,4a,9b-Tetrahydrodibenzofuran-4-ols and Its Application to the Second-Generation Synthesis of (.+-.)-Linderol A.

✍ Masayuki Yamashita; Tomoki Inaba; Masaki Nagahama; Takashi Shimizu; Sachiko Kosa 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

Novel stereoconvergent transformation of

Novel stereoconvergent transformation of 1,2a-disubstituted 1,2,2a,8b-tetrahydro-3H-benzo[b]cyclobuta[d]pyran-3-ones to 1,3-disubstituted 1,2,4a,9b-tetrahydrodibenzofuran-4-ols and its application to the second-generation synthesis of (±)-linderol A

✍ Yamashita, Masayuki; Inaba, Tomoki; Nagahama, Masaki; Shimizu, Takashi; Kosaka, 📂 Article 📅 2005 🏛 Royal Society of Chemistry 🌐 English ⚖ 326 KB