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Instability of chromosome 8 as an indicator of aggressive tumor phenotype in pancreatic cancer

✍ Scribed by Norihiro Sato; Kazuhiro Mizumoto; Naoki Maehara; Masaki Shono; Eishi Nagai; Masao Tanaka


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
185 KB
Volume
76
Category
Article
ISSN
0022-4790

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## Abstract Loss of heterozygosity (LOH) on the short arm of chromosome 8 occurs at high frequencies in many tumor types, including colorectal carcinoma. We have previously used microcell‐mediated chromosome transfer (MMCT) to map an approximately 7.7 Mb colorectal cancer suppressor region (CRCSR)