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Insights into the molecular regulation of FasL (CD178) biology

✍ Scribed by Marcus Lettau; Maren Paulsen; Hendrik Schmidt; Ottmar Janssen

Book ID
113582874
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
706 KB
Volume
90
Category
Article
ISSN
0171-9335

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## Abstract The transmembrane protein CD133 and its extracellular epitope AC133 are controversial cancer markers. In glioma, AC133 demarcates a subpopulation of stem‐like tumor cells, so‐called cancer stem cells (CSCs), which seem to drive tumor formation and are highly resistant to conventional ch