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Insights into the Dynamics of HIV-1 Protease: A Kinetic Network Model Constructed from Atomistic Simulations

✍ Scribed by Deng, Nan-jie; Zheng, Weihua; Gallicchio, Emillio; Levy, Ronald M.

Book ID
111642521
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
985 KB
Volume
133
Category
Article
ISSN
0002-7863

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## Abstract The SL1 stem‐loop is the dimerization initiation site for linking the two copies of the RNA forming the HIV‐1 genome. The 26 nucleotides stem contains a defect consisting on a highly conserved G‐rich 1‐3 asymmetrical internal loop, which is a major site for nucleocapsid protein binding.