𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

✍ Scribed by Matthew C Franklin; Kendall D Carey; Felix F Vajdos; Daniel J Leahy; Abraham M de Vos; Mark X Sliwkowski

Book ID
114413422
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
818 KB
Volume
5
Category
Article
ISSN
1535-6108

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mechanistic and signaling analysis of Mu
Mechanistic and signaling analysis of Muc4–ErbB2 signaling module: New insights into the mechanism of ligand-independent ErbB2 activity
✍ Goldi A. Kozloski; Coralie A. Carothers Carraway; Kermit L. Carraway πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 252 KB

## Abstract The membrane mucin Muc4 is aberrantly expressed in numerous epithelial carcinomas and is currently used as a cancer diagnostic and prognostic tool. Muc4 can also potentiate signal transduction by modulating differential ErbB2 phosphorylation in the absence and in the presence of the Erb