✦ LIBER ✦

Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1)

✍ Scribed by Ajit Kumar; Kuan-Teh Jeang

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 183 KB
Volume: 216
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.21488

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Recent findings suggest that mammalian microRNAs (miRNAs) may influence viral replication in host cells. Studies on HIV‐1 infection have contributed in part to the development of this notion. Herein, we review, in brief, some of the evidence supportive of an interplay between human miRNAs and HIV‐1 in cells. Several cellular miRNAs potentially act to restrict HIV‐1 replication, and the virus has countermeasures to evade such restriction. J. Cell. Physiol. 216: 327–331, 2008. © 2008 Wiley‐Liss, Inc.

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