Retroviral vector production using suspe
โ
Karim Ghani; Alain Garnier; Helene Coelho; Julia Transfiguracion; Pierre Trudel;
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 217 KB
Recombinant retroviruses are now an established tool for gene delivery. Presently they are mainly produced using adherent cells. However, due to the restrictive nature of adherent cell culture, this mode of production is hampered by low cell-specific productivity and small production units. The larg