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Insight into early events in the aggregation of the prion protein on lipid membranes

✍ Scribed by Narinder Sanghera; Marcus J. Swann; Gerry Ronan; Teresa J.T. Pinheiro

Book ID: 116274885
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 547 KB
Volume: 1788
Category: Article
ISSN: 0005-2736
DOI: 10.1016/j.bbamem.2009.08.005

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## Abstract Under favorable conditions, many proteins can assemble into macroscopically large aggregates such as the amyloid fibrils that are associated with Alzheimer's, Parkinson's, and other neurological and systemic diseases. The overall process of protein aggregation is characterized by initia