**Metabolische Prozesse** lassen sich mithilfe massenspektrometrischer „Fingerabdrücke“ von Atemluft durch eine Kombination aus extrahierender Elektrosprayionisations(EESI)‐ und Quadrupol‐TOF(QTOF)‐Massenspektrometrie in Echtzeit verfolgen. Für diese schnelle On‐line‐ und In‐vivo‐Methode sind weder
✦ LIBER ✦
Inside Cover: Rapid In Vivo Fingerprinting of Nonvolatile Compounds in Breath by Extractive Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry (Angew. Chem. Int. Ed. 4/2007)
✍ Scribed by Huanwen Chen; Arno Wortmann; Weihua Zhang; Renato Zenobi
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 31 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0044-8249
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✦ Synopsis
Metabolic dynamics can be followed in real time by mass spectral fingerprints of breath by extractive electrospray ionization (EESI) quadrupole TOF mass spectrometry on a commercial instrument. Neither sample pretreatment nor hardware modifications are necessary for this rapid, online, and in vivo method. Furthermore, selective ion/molecule reactions in the EESI interface can lead to the detection of interesting compounds. For more details see the Communication by R. Zenobi and co‐workers on page 580ff.
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