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Inside Cover: North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity (ChemMedChem 8/2009)

✍ Scribed by Pamela L. Russ; Maria J. Gonzalez-Moa; B. Christie Vu; Dina M. Sigano; James A. Kelley; Christopher C. Lai; Jeffrey R. Deschamps; Stephen H. Hughes; Victor E. Marquez

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 471 KB
Volume: 4
Category: Article
ISSN: 1860-7179
DOI: 10.1002/cmdc.200990036

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North- and South-Bicyclo[3.1.0]Hexene Nu

North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity

✍ Pamela L. Russ; Maria J. Gonzalez-Moa; B. Christie Vu; Dina M. Sigano; James A. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB

## Abstract __The syntheses of new conformationally locked North‐ and South‐bicyclo[3.1.0]hexene nucleosides is reported. The North analogues were synthesized by a convergent approach from the known (1__S__,2__R__,5__R__)‐5‐[(__tert__‐butyldiphenylsilyloxy)methyl]bicyclo[3.1.0]hex‐3‐en‐2‐ol by Mits