Insensitivity to glutamate neurotoxicity mediated by NMDA receptors in association with delayed mitochondrial membrane potential disruption in cultured rat cortical neurons

Chronic vitamin D3 treatment protects ag

Chronic vitamin D3 treatment protects against neurotoxicity by glutamate in association with upregulation of vitamin D receptor mRNA expression in cultured rat cortical neurons

✍ Hideo Taniura; Minoru Ito; Noriko Sanada; Nobuyuki Kuramoto; Yu Ohno; Noritaka N 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 630 KB

## Abstract The vitamin D receptor (VDR) is believed to mediate different biologic actions of vitamin D~3~, an active metabolite of vitamin D, through regulation of gene expression after binding to specific DNA‐response element (VDRE) on target genes. To further understand roles of both vitamin D~3