Insensitivity of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity to low-density lipoprotein in concanavalin-A-resistant Chinese-hamster ovary cells
β Scribed by Thor Borgford; David N. Burton
- Book ID
- 112482514
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 384 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0144-8463
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When the disulfide of 2-mercaptoethanol (ESSE) is added to the medium of cultured Chinese hamster ovary (CHO) cells, a time and concentration dependent release of 2-mercaptoethanol to the medium is observed. The reduction of ESSE to 2-mercaptoethanol by cells is a saturable process, the rate being a