๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Insecticide action at the GABA-gated chloride channel: Recognition, progress, and prospects

โœ Scribed by Dr. John E. Casida


Book ID
102748275
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
597 KB
Volume
22
Category
Article
ISSN
0739-4462

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5-tert-Butyl-2-(4-ethynylphenyI)pyrimidine and the corresponding 2,5disubstituted-4H-1,3-thiazine block the GABA-gated chloride channel at c.20 and c.200 nM, respectively, measured as 50% inhibition of the binding of 1- ) in house fly and mouse brain membranes, and they are also toxic to topically-