Insect cytochrome P-450
โ Scribed by Moises Agosin
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 904 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0300-8177
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The field of P450 research is progressing rapidly. The active sites of structurally characterized bacterial P450 enzymes have been rationally re-engineered to alter both substrate specificity and selectivity of substrate oxidation. Many human P450 enzymes have been functionally expressed and new met
Of the family of P-450 cytochromes occurring in rabbit liver microsomes, only isozyme 3a (P-450ALC) is induced by alcohol administration and is effective in catalyzing the reaction: ethanol +02+NADPH+H+----acetaldehyde +2H2O+NADP+. As judged by immunochemical quantitation, P-450ALC is also induced i