Inorganic Polyphosphates in Eukaryotic Cells

✍ Scribed by Tatiana Kulakovskaya, Evgeny Pavlov, Elena N. Dedkova (eds.)

Publisher: Springer International Publishing
Year: 2016
Tongue: English
Leaves: 242
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. The book describes the evolution of PolyPs, their role in lower eukaryotes and their involvement in various processes in the human organism, as well as its use in biomaterials such as bioactive glass and engineered bone tissue.

The aim of this book is to summarize the data of the past decade on the functional role of inorganic polyphosphates in eukaryotes and discuss their biological role also in context of common human diseases. The book will provide a modern concept of the functional significance of these biopolymers, useful for researchers in cell biology, biochemistry, molecular biology and biomedicine alike.

✦ Table of Contents

Front Matter....Pages i-viii
Front Matter....Pages 1-1
The Role of Inorganic Polyphosphates in Stress Response and Regulation of Enzyme Activities in Yeast....Pages 3-14
Yeast Polyphosphatases PPX1 and PPN1: Properties, Functions, and Localization....Pages 15-33
Polyphosphate Storage and Function in Acidocalcisomes....Pages 35-48
Inorganic Polyphosphates in Mycorrhiza....Pages 49-60
Functions of Inositol Polyphosphate and Inorganic Polyphosphate in Yeast and Amoeba....Pages 61-78
Front Matter....Pages 79-79
Methods of Inorganic Polyphosphate (PolyP) Assay in Higher Eukaryotic Cells....Pages 81-89
Inorganic Polyphosphates in the Mitochondria of Mammalian Cells....Pages 91-114
Role of Inorganic Polyphosphate in the Cells of the Mammalian Brain....Pages 115-121
Inorganic Polyphosphate Functions and Metabolism in Insects....Pages 123-138
Inorganic Polyphosphate and Its Chain-Length Dependency in Tissue Regeneration Including Bone Remodeling and Teeth Whitening....Pages 139-158
Inorganic Polyphosphate in Blood Coagulation....Pages 159-176
Influence of Condensed Phosphates on the Physical Chemistry of Calcium Phosphate Solids....Pages 177-205
Inorganic Polyphosphate Is an Essential Structural and Functional Component of the Mammalian Ion Channel TRPM8....Pages 207-215
Inorganic Polyphosphate in Tissue Engineering....Pages 217-239
Back Matter....Pages 241-243

✦ Subjects

Molecular Medicine;Eukaryotic Microbiology;Bioorganic Chemistry;Polymer Sciences;Biochemical Engineering;Hematology

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