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Inorganic arsenic impairs proliferation and cytokine expression in human primary T lymphocytes

✍ Scribed by Claudie Morzadec; Fidaa Bouezzedine; Mélinda Macoch; Olivier Fardel; Laurent Vernhet


Book ID
113934179
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1010 KB
Volume
300
Category
Article
ISSN
0300-483X

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## Abstract Inorganic arsenic is an environmental contaminant toxic for key immune cells. We recently reported that low micromolar concentrations of arsenic trioxide (As~2~O~3~) alter functions and differentiation gene program of human macrophages. Particularly, prolonged treatment with As~2~O~3~ c