Circadian variations in the pharmacokine
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Qing-Ri Cao; Tae-Wan Kim; Jun Shik Choi; Beom-Jin Lee
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Article
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2005
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John Wiley and Sons
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English
โ 129 KB
๐ 2 views
## Abstract Circadian variations in the pharmacokinetics, tissue distribution and urinary excretion of nifedipine were examined in fasted rats after administering a single oral dose at three different dosing times (08:00 am, 16:00 pm, 00:00 am). The plasma concentrations, the areas under the plasma