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Innate Immunity: Toll-Like Receptors and Some More

✍ Scribed by Fleer, André; Krediet, Tannette G.

Book ID: 120570487
Publisher: S. Karger AG
Year: 2007
Tongue: English
Weight: 439 KB
Volume: 92
Category: Article
ISSN: 1661-7800
DOI: 10.1159/000102054

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Functional characterization of Toll-like receptors (TLRs) has established that innate immunity is a skillful system that detects invasion of microbial pathogens. Recognition of microbial components by TLRs initiates signal transduction pathways, which triggers expression of genes. These gene product