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Innate Immunity confounds the clinical efficacy of small interfering RNAs (siRNAs)

✍ Scribed by Rossi, J J

Book ID: 109855281
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 85 KB
Volume: 16
Category: Article
ISSN: 0969-7128
DOI: 10.1038/gt.2009.26

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## Abstract Silencing of a specific mRNA using double stranded RNA oligonucleotides represents one of the newest technologies for suppressing a specific gene product. Small interfering RNA (siRNA) are 21 nucleotides long, double stranded RNA fragments that are identical in sequence to the target mR