Innate immunity and intestinal microbiota in the development of Type 1 diabetes
✍ Scribed by Wen, Li; Ley, Ruth E.; Volchkov, Pavel Yu.; Stranges, Peter B.; Avanesyan, Lia; Stonebraker, Austin C.; Hu, Changyun; Wong, F. Susan; Szot, Gregory L.; Bluestone, Jeffrey A.
- Book ID
- 109897731
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 354 KB
- Volume
- 455
- Category
- Article
- ISSN
- 0028-0836
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## Abstract Two arms of the immune system, innate and adaptive immunity, differ in their mode of immune recognition. The innate immune system recognizes a few highly conserved structures on a broad range of microorganisms. On the other hand, recognition of self or autoreactivity is generally confin
## Abstract ## Objective The contribution of innate immunity responsible for beta‐cell destruction in fulminant type 1 diabetes (FT1D) and slowly progressive insulin‐dependent diabetes mellitus (SPIDDM) is unclear. ## Research Design and Methods Islet‐cell expression of Toll‐like receptors (TLRs