Enhanced CBir1-specific innate and adapt
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Chong Shen; Carol J. Landers; Carrie Derkowski; Charles O. Elson; Stephan R. Tar
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Article
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2008
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John Wiley and Sons
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English
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Background: CBir1 is a dominant antigen with a role in innate and adaptive immunity in mouse models of colitis and antibodies to CBir1 are associated with severe human Crohn's disease (CD). Our aim was to determine whether CBir1 stimulates innate and antigen-specific T-cell responses in CD. We demon