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Injury to primary cultures of rat heart endothelial cells by hypoxia and glucose deprivation

โœ Scribed by Daniel Acosta; Cheng-Pei Li

Book ID
112797693
Publisher
Society for In Vitro Biology
Year
1979
Tongue
English
Weight
863 KB
Volume
15
Category
Article
ISSN
1475-2689

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To characterize the role of oxidative stress in cultured rat sinusoidal endothelial cells, we studied the production of superoxide after reoxygenation, the relationship of reduced glutathione (GSH) levels to cell injury, and the protective efficacy of antioxidants. Hypoxia (pO 2 1-2 mm Hg) was achie