Injury and membrane potentials in frog muscle after depleting potassium and producing other changes by soaking in potassium free salt solution or distilled water
✍ Scribed by Tobias, Julian M.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1950
- Tongue
- English
- Weight
- 631 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0095-9898
No coin nor oath required. For personal study only.
✦ Synopsis
ONE FIGL'BE
The role wliicli niaiiy investigators (Beriistein, '02 ; Xac-Donald, '05 ; Cowan, '34 ; Boyle and Conway, '41 ; Rlianes, '44; Ling, personal conmiunication, '50) explieitlJr or implicitly assign to ail iiitracellulnr-extracellular potassium concentration gradient as the esclusim generator of injury and meiiibranc potentials in nerve aiid muscle depends f o r its validation primarily on a more-or-less satisfactory demonstration oS a straight line relationship between EMF. and the logarithm of the extraccllular K concmtration. Several investigators (Curtis aiid Cole, '42 ; Steinbach, '44)' h o ~-e r c r , using the squid asoiie, have either fomd a curvilinear relation between these two quantities or that the E.3I.F. becomes a linear function of log I<,,, only at and above high outside concentrations, arid others (Beutncr, '33 ;