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Initiation of UV mutagenesis in Saccharomyces cerevisiae

✍ Scribed by KILBEY, B. J.; BRYCHCY, TERESA; NASIM, A.

Book ID
109710562
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
352 KB
Volume
274
Category
Article
ISSN
0028-0836

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✍ Prakash, Louise ;Hinkle, David ;Prakash, Satya πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 816 KB

A DNA replication mutant of yeast, cdc8, was found to decrease UV-induced reversion of lys2-1, arg4-17, tyr1 and ura1. This effect was observed with all three alleles of cdc8 tested. Survival curves obtained following UV irradiation in cdc8 rad double mutants show that cdc8 is epistatic to rad6, as