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Initiation of neural induction by FGF signalling before gastrulation

✍ Scribed by Streit, Andrea; Berliner, Alyson J.; Papanayotou, Costis; Sirulnik, Andrés; Stern, Claudio D.

Book ID
109770169
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
374 KB
Volume
406
Category
Article
ISSN
0028-0836

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## Background The molecular mechanism that initiates the formation of the vertebrate central nervous system has long been debated. Studies in __Xenopus__ and mouse demonstrate that inhibition of BMP signaling is sufficient to induce neural tissue in explants or ES cells respectively, whereas studie