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Initiation of DNA Synthesis in a System of Synchronized L-Cells: Rhythmicity of Thymidine Kinase Activity

✍ Scribed by C. MITTERMAYER; R. BOSSELMANN; V. BREMERSKOV

Book ID
115111634
Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
350 KB
Volume
4
Category
Article
ISSN
1432-1327

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Formation of thymidine kinase and deoxyc
Formation of thymidine kinase and deoxycytidylate deaminase in synchronized cultures of chinese hamster cells temperature-sensitive for DNA synthesis
✍ Saul Kit; George N. Jorgensen πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 501 KB

## Abstract Cytosol thymidine kinase (TK) and deoxycytidylate (dCMP) deaminase formation was investigated in synchronized cultures of K12 Chinese hamster cells which have a temperature‐sensitive lesion affecting the initiation of DNA synthesis. Enzyme formation was found to be cycloheximide‐sensiti