Recent multiwavelength observations, modelling results and theoretical developments indicate the importance of twisted magnetic conÿgurations in solar active regions (ARs) in the initiation of coronal mass ejections (CMEs). Through multiwavelength analysis of a few representative events we make an attempt to provide constraints for CME models. The two events presented here in detail start with the expansion of sigmoids (S-or inverse S-shaped loops) observed in soft X-rays. Both events (on 25 October 1994 and 14 October 1995) occurred before the launch of the SOHO spacecraft, but indirect evidences (i.e. signatures of an outward propagation traced up to ≈ 20 solar radii and an associated magnetic cloud) suggest that both of them were related to CMEs. We show evidence that sigmoids are the coronal manifestations of twisted magnetic ux tubes, which start expanding presumably due to a loss of equilibrium. It is noteworthy that the analysed CMEs occurred in a complex (not simply bipolar) magnetic environment and in all cases we found evidences of the interaction (magnetic reconnection) with the surrounding ÿelds. We propose a scenario for sigmoid expansion related CME events and suggest that twisted magnetic conÿgurations are good candidates for being source regions of CMEs.