Initiation-development modelling of allelic losses on chromosome 9 in multifocal bladder cancer
✍ Scribed by J Louhelainen; H Wijkström; K Hemminki
- Book ID
- 117656863
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 1024 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0959-8049
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Allelic loss on chromosome 9 is the most frequent and earliest genetic event in bladder carcinogenesis, and its detection in urine samples would be useful for detecting bladder cancer. A highly sensitive method to detect loss of heterozygosity (LOH) at 5 polymorphic loci on chromosome 9p and 9q was
## Abstract Patients who receive curative treatment for lung cancer can develop additional lung tumors that may or may not be related to the original tumor and thus require different clinical management. If a subsequent tumor has a pattern of allele loss, revealed by allelotype analysis, overlappin